Properties of cells; domains of living organisms

Domains of organisms; sources of cellular energy

Comparison of procaryotic and eucaryotic cells

Protein structure

Protein domains; regulation of protein activity

Protein folding and degradation; cellular topology; compartments in cells

Protein sorting; signal peptides; nuclear structure and nuclear import

Protein sorting: nuclei and mitochondria

Endoplasmic reticulum (~ last 15 minutes of lecture; beginning not recorded)

ER: cotranslational and post-translational protein import

ER: topology of membrane proteins, protein glycosylation, protein folding

Vesicular transport; structure and assembly of coated vesicles

Regulation of vesicular transport

Mitochondria structure and function

Mitochondria - ATP synthesis; transport of metabolites

Electron transport and proton pumping; chloroplasts

Photosythesis; organelle gene expression

Evolution of oxidative phosphorylation; introduction to cell signaling

Cell signaling classification; nuclear hormone receptors

Signal transduction pathways; G protein coupled receptors

Receptor tyrosine kinase signaling

Regulated proteolysis/Wnt signaling; signaling in plants; introduction to cytoskeleton

Dynamic instability of cytoskeletal filaments; intermediate filaments

Dynamic instability of cytoskeletal filaments; intermediate filaments

Accessory proteins regulating cytoskeleton function; motor proteins

Molecular motors